Simultaneous MR and PET in clinical use.
The simultaneous acquisition of MR and PET data across the whole body allows for breathtaking images. Enabling new insights into the progress of disease. Unlocking new paths to treatment. Opening new areas of research. Fully supporting you from detection and planning through monitoring and follow-up.
Deliver exceptional quality simultaneously for MR and PET
Combining anatomical, functional, and metabolic information with exceptional image quality, Biograph mMR ensures that you get the whole picture in one simultaneous scan.
How can you receive outstanding image quality?
A new portfolio of Biograph mMR coils and MR-only coils deliver exceptional image quality simultaneously for MR and PET:
- mMR Head/Neck, A Tim coil
- mMR Head, A Tim coil
- mMR Spine, A Tim coil
- mMR Body, A Tim coil (up to 5 at a time)
- mMR Breast, A Tim coil (for imaging and biopsy)
- Special Purpose coil
- 4-channel flex coil, large and small
Reconstruction point-spread function (PSF) for better PET image quality, improved resolution1, and visual improvements in signal-to-noise2.
"The whole-body PET-MRI gives a holistic picture of the entire body […] which you really need in cancer management and many other areas."3
MD Neurosurgeon, Apollo Hospital
New Delhi, India
Optimize accuracy with simultaneous motion compensation
A large number of patients – with dementia, motion disorders, brain tumors or un-sedated children – can benefit from molecular MR. Biograph mMR, offers new motion-compensation strategies for PET, based on real-time MR information.
How can we help to ensure maximum accuracy and motion compensation?
With Brain COMPASS
MR-based PET motion compensation for sharper images, better contrast, and improved quantification.
“Brain COMPASS allowed us to examine patients suffering from severe seizures e.g. due to brain tumors. For these patients we can now get diagnostic image quality [...] Without this new feature it was difficult or did not generate satisfying results due to patient motion.”3
MD, Assistant Medical Director, Department of Nuclear Medicine
University Hospital Essen, Germany
Routine respiratory gating of PET and MRAC data for sharp images with minimal setup time.
Ultra-short echo based bone segmentation for attenuation correction (AC) in the head.
Differentiate with molecular MRI services
Differentiate your institute through advanced technology, allowing you to stay at the cutting edge of clinical service and research, enabling growing patient referrals and a steady stream of funding from research grants.
How can you differentiate your institution?
- Soft-tissue contrast, functional and molecular information in one exam
- Precise spatial correlation
- Temporal co-registration
- MR-based motion management
- Higher patient comfort
- Time-saving single exam and faster results
- Reduced dose relative to other hybrid PET systems4
- Only one stress injunction or sedation
- New clinical fields and additional patients
- Cutting-edge research and application for new grants
- Less space and personnel required
- Higher throughput, easier scheduling and organization
"The PET-MRI system has allowed a lot of our complex research to become more feasible. As a result, a number of our research grants have been funded."3
Professor Pamela Woodard
MD, Director Center for Clinical Imaging Research
Washington University, St. Louis , MO, USA
1Results shown to characterize HD•PET algorithm in a non-clinical, non-NEMA setting. Results show average of transverse radial and transverse tangential FWHM as a function of distance from isocenter. Measurements were taken with a point source suspended in air at radial positions from 1 centimeter outwards in 4 centimeter steps. Data shown is to a diameter of 50 cm. The current definition of resolution within the NEMA protocol defines the ability to distinguish 2 closely spaced lesions. This ability cannot be derived from this measurement as HD•PET
is a non-linear reconstruction method. The point source data were reconstructed both with a standard filtered back projection algorithm using FORE rebinning (conventional) and an iterative algorithm using TrueX (HD•PET) with 6 iterations and 21 subsets. The FWHM measurements for TrueX were estimated by calculating a variance using 5 points centered on the peak of the experimental data with a 2 millimeter pixel size. Variance was converted to a FWHM assuming a Gaussian model. This method accounts for the small number of pixels within the FWHM which precludes the use of standard NEMA methodology.
2Conventional reconstructed images compared to images reconstructed with HD•PET.
4S.C. Chawla, N. Federman, D. Zhang, K. Nagata, S. Nuthakki, M. McNitt-Gray and M.I. Boechat, "Estimated cumulative radiation dose from PET/CT in children with malignancies: 5-year retrospective review." (2010) Pediatric Radiology 40:681-686
Data acquired from December 2002 to October 2007, institutions clinical practice is to perform a diagnostic CT study matching the PET FoV, in addition breath-hold non-contrast CT chest study's are performed in selected patients as needed to evaluate for metastatic disease in the lungs and are included in findings.
MR scanning has not been established as safe for imaging fetuses and infants under two years of age. The responsible physician must evaluate the benefit of the MRI examination in comparison to other imaging procedures.